BioLM
Solutions
Apply the BioLM platform to real molecular design objectives — from optimization campaigns to discovery programs.
ANTIBODY
EVQLVE
SGGGLV
QPGGSL
RLSCAA
SYIHWV
RQAPGK

What can you design with BioLM?
BioLM for enzyme optimization
Optimize properties such as enzyme thermostability, solubility, expression, all while maintaining or increasing activity.
Learn about how we helped an early stage biotech with no prior data fast-track their enzyme optimization and achieve a 3-fold productivity improvement within two months.
Explore objectives — and run them yourself, with BioLM, or through agents.
How It Works
Every solution can be run on your own, with BioLM, or through agents — using the same platform primitives.
A structured design → test → learn process that compounds performance over successive rounds.
STEP 01
Define the objective
Align on the biological objective and constraints - target metrics (e.g., binding, stability, expression, developability), sequence/structure constraints, and what success looks like for the next round - plus the assay plan used to measure it.
STEP 02
Design & prioritize candidates
BioLM Protocols generate and evaluate candidate molecules with biological language models and model-based scoring, then prioritize a tractable experimental set using multi-parameter ranking and constraint-aware selection.
STEP 03
Lab-in-the-Loop testing
Validate candidates through partner or customer labs (and CROs as needed), capturing assay outputs and linking results back to each design so every datapoint is usable for downstream learning and decision-making.
STEP 04
Learn & iterate
Register experimental results in BioLM, update selection criteria, and use lab data to fine-tune/customize biological language models and predictors - so the next round designs reflect what the lab just taught us.
STEP 05
Scale & compound
Operationalize what works with repeatable Protocols and tuned models, compounding performance across rounds until you reach validated, developable, commercially valuable molecules.
Frequently Asked Questions
We help you understand how AI solves your design objective
“With BioLM, we found a 10ºC improvement in optimal temperature in our first library of <100 variants. This led to a 4-fold increase in catalyst productivity in <2 months from project start. We’re excited for our next round of evolution!”
Trevor, Co-founder & CTO, Caravel Bio“In our early stages of enzyme selection, BioLM walked us through the most viable AI/ML options and provided numerous optimized sequences at a competitive price. Their in-depth understanding of the field truly sets them apart in the market.”
Arzu, Co-founder & CEO, Rhea's FactoryAccelerate yourLead generation
BioLM offers tailored AI solutions to meet your experimental needs. We deliver top-tier results with our model-agnostic approach, powered by our highly scalable and real-time GPU-backed APIs and years of experience in biological data modeling, all at a competitive price.


